Pre-implantation genetic diagnosis (PGD) or screening (PGS) is the latest cutting edge technology available in the field of infertility management.
Genetic diseases are no more rare now. They have profound financial and psychological implications for families. It is a traumatic experience for parents to discover that their newborn is suffering from a genetic disease. Also, people who themselves have genetic disorders are extremely concerned about not passing these diseases to their children
Up till recently the maximum parents and doctors could do was to check patients who were already pregnant for these diseases and go for termination of pregnancy. Other interventions are limited during pregnancy which can have adverse psychological impact on pregnant women and families.
Now a days, we are fortunate to have advanced Genetic services like Pre-implantation Genetic testing (PGT) and Genetic Carrier screening which can prevent the transmission of Genetic disorders in future generations and reduce the burden of these serious conditions. It is a godsend for prospective parents as this technology is extremely useful in stopping the transmission of these disorders.
How it is done: An IVF or test tube baby procedure is done for these parents and the embryos formed are tested for genetic diseases. Only the healthy embryos are then carried forward for pregnancy. They are implanted back into the mother’s womb and the pregnancy proceeds as normal.
Diseases such as Down’s syndrome and single gene disorders can be eliminated from the family line by this way. PGT is now being performed for almost every Genetic disorder. Disorders like Thalassemia, Sickle cell anemia, Hemophilia, Duchenne muscular dystrophy, Myotonic dystrophy, Spinal muscular atrophy, Cystic fibrosis and many more. By this technique, risk estimation for genetic disorder in future children and reproductive planning can be done in advance. PGT is good choice in these cases if gene defect is identified.
All these facilities are available at our centre and the genetic diseases program is running successfully for over 2 years now. Jindal IVF is the first centre in the region to offer this program.