In India, Human Papilloma Virus (HPV) s an important cause of cancer of cervix, vagina and vulva as well as the anus, mouth or throat in women. Most cases of these HPV related cancers can be prevented by HPV vaccine. HPV vaccine offers best possible protection when done in adolescent age before exposure to HPV infection. Therefore, it is recommended for young teenage girls who are 11-12 years old. Most of the professional bodies all over the world including Federation of Obstetrics and Gynaecological Societies of India recommend this vaccine for HPV cancer prevention. The HPV vaccine is shown to be extremely effective in several studies. Since 2006, millions of doses of HPV vaccine have been distributed across the world. HPV vaccine is safe. Most side effects are mild such as pain or redness in the arm. HPV vaccine has not been associated with any long term side effects. The vaccine is administered in 3 doses for best protection. Consult your doctor for further information.